Publications in 2013

Becker, M., Börngen, K., Nomura, T., Battle, A. R., Marin, K., Martinac, B., Krämer, R. (2013)

Glutamate efflux mediated by Corynebacterium glutamicum MscCG, Escherichia coli MscS, and their derivatives
BBA 1828: 1230-40

Donovan, C., A. Schauss, et al. (2013).

Chromosome Segregation Impacts on Cell Growth and Division Site Selection in Corynebacterium glutamicum
PLoS One 8(2):e55078

Lindner, S. N., D. P. Petrov, et al. (2013)

Phosphotransferase system- (PTS-) mediated glucose uptake is repressed in phosphoglucoisomerase-deficient Corynebacterium glutamicum strains
Appl Environ Microbiol, ahead of print

Uhde, A., J. W. Youn, et al. (2013)

Glucosamine as carbon source for amino acid-producing Corynebacterium glutamicum
Appl Microbiol Biotechnol 97(4): 1679-1687

Chi, B.K., Busche, T., Laer, K.V., Basell, K., Becher, D., Clermont, L., Seibold, G.M., Persicke, M., Kalinowski, J., Messens, J., et al. (2013)

Protein S-Mycothiolation Functions as Redox-Switch and Thiol Protection Mechanism in Corynebacterium glutamicum Under Hypochlorite Stress
Antioxid Redox Signal.

Henrich, A., Kuhlmann, N., Eck, A.W., Krämer, R., and Seibold, G.M. (2013)

Maltose uptake by the novel ABC transport system MusEFGK2I causes increased expression of ptsG in Corynebacterium glutamicum
J Bacteriol 195, 2573-2584.

Seibold, G.M., and Eikmanns, B.J. (2013)

Inactivation of the phosphoglucomutase gene pgm in Corynebacterium glutamicum affects cell shape and glycogen metabolism
Biosci Rep 33: 645-654

Publications in 2012

Donovan, C., Sieger, B., Krämer, R., Bramkamp, M. (2012)

A synthetic Escherichia coli system identifies a conserved origin tethering factor in Actinobacteria
Mol. Microbiol.84(1): 105–16

Gruteser, N., K. Marin, et al. (2012)

Sialic acid utilization by the soil bacterium Corynebacterium glutamicum
FEMS Microbiol Lett 336(2):131-8

von Berlepsch, S., H. H. Kunz, et al. (2012)

The acyl-acyl carrier protein synthetase from Synechocystis sp. PCC 6803 mediates fatty acid import
Plant Physiol 159(2):606-7

S.C.T. Nicklisch, D. Wunnicke, I.V. Borovykh, S. Morbach, J.P. Klare, H.-J. Steinhoff, R. Krämer (2012)

Conformational changes of the betaine transporter BetP from Corynebacterium glutamicum studied by pulse EPR spectroscopy
BBA 1818(3): 359–66

Schneider, J., Peters-Wendisch, P., Stansen, K. C., Götker, S., Maximow, S., Krämer, R. and Wendisch, V. F. (2012)

Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum
BMC Microbiol.12:6

Laslo, T., Zaluskowski, P.v., Gabris, C., Lodd, E., Rückert, C., Dangel, P., Kalinowski, J., Auchter, M., Seibold, G. and Eikmanns, B. J. (2012)

Arabitol Metabolism of Corynebacterium glutamicum and its Regulation by AtlR
J. Bacteriol. 194(5):941-55

Koch-Koerfges, A., Kabus, A., Ochrombel, I., Marin, K., Bott, M. (2012)

Physiology and global gene expression of a Corynebacterium glutamicum F1FO-ATP synthase mutant devoid of oxidative phosphorylation
BBA 1817(2):370–80

Publications in 2011

Perez, C., Khafizov, K., Forrest, L. R., Krämer, R. & Ziegler, C. (2011)

The role of trimerization in the osmoregulated betaine transporter BetP
EMBO reports 12:804–10

Ochrombel, I., Becker, M., Krämer, R., Marin, K. (2011)

Osmotic stress response in C. glutamicum: impact of channel- and transporter-mediated potassium accumulation
Arch. Microbiol. 193(11):787-96

N. Lindner, S N., Seibold, G. M., Henrich, A., Krämer, R., and Wendisch, V. F. (2011)

Phosphotransferase System-Independent Glucose Utilization in Corynebacterium glutamicum by Inositol Permeases and Glucokinases
Appl. Environ. Microbiol. 77(11):3571-81

Ochrombel, I., Ott, L., Krämer, R., Burkovski, A., Marin, K. (2011)

Impact of improved potassium accumulation on pH homeostasis, membrane potential adjustment and survival of Corynebacterium glutamicum
BBA 1807(4):444–50

Seibold, G. M., Breitinger, K. J., Kempkes, R., Both, L., Krämer, M., Dempf, S. and Eikmanns, B. J. (2011)

The glgB-encoded glycogen branching enzyme is essential for glycogen accumulation in Corynebacterium glutamicum
Microbiol. 157(11):3243-51

Forrest, L. R., Krämer, R., Ziegler, C. (2011)

The structural basis of secondary active transport mechanisms
BBA 1807(2):167–88

Fink, P., C. Pflitsch, et al. (2011)

Dietary essential amino acids affect the reproduction of the keystone herbivore Daphnia pulex
PLoS One 6(12): e28498

Huhn, S., E. Jolkver, et al. (2011)

Identification of the membrane protein SucE and its role in succinate transport in Corynebacterium glutamicum
Appl Microbiol Biotechnol 89(2): 327-335

Lindner, S. N., G. M. Seibold, et al. (2011)

Impact of a new glucose utilization pathway in amino acid-producing Corynebacterium glutamicum
Bioeng Bugs 2(5):291-5

Novak, J. F., M. Stirnberg, et al. (2011)

A novel mechanism of osmosensing, a salt-dependent protein-nucleic acid interaction in the cyanobacterium Synechocystis Species PCC 6803
J Biol Chem 286(5):3235-41

Perez, C., C. Koshy, et al. (2011)

Substrate specificity and ion coupling in the Na+/betaine symporter BetP
EMBO J 30(7):1221-29

Tsai, C. J., K. Khafizov, et al. (2011)

Structural asymmetry in a trimeric Na+/betaine symporter, BetP, from Corynebacterium glutamicum
J Mol Biol 407(3): 368-81

Publications in 2010

Blombach, B. and G. M. Seibold (2010)

Carbohydrate metabolism in Corynebacterium glutamicum and applications for the metabolic engineering of L-lysine production strains
Appl Microbiol Biotechnol 86(5): 1313-22

Borngen, K., A. R. Battle, et al. (2010)

The properties and contribution of the Corynebacterium glutamicum MscS variant to fine-tuning of osmotic adaptation
Biochim Biophys Acta 1798(11): 2141-49

Donovan, C., A. Schwaiger, et al. (2010)

Subcellular localization and characterization of the ParAB system from Corynebacterium glutamicum
J Bacteriol 192(13): 3441-51

Krämer, R., S. Nicklisch, et al. (2010)

Use of liposomes to study cellular osmosensors
Methods Mol Biol 606: 21-30

Krause, F. S., A. Henrich, et al. (2010)

Increased glucose utilization in Corynebacterium glutamicum by use of maltose, and its application for the improvement of L-valine productivity
Appl Environ Microbiol 76(1):370-4

Prabhakar, V., T. Lottgert, et al. (2010)

Phosphoenolpyruvate provision to plastids is essential for gametophyte and sporophyte development in Arabidopsis thaliana
Plant Cell 22(8): 2594-617

Seibold, G. M., C. T. Hagmann, et al. (2010)

The transcriptional regulators RamA and RamB are involved in the regulation of glycogen synthesis in Corynebacterium glutamicum
Microbiol 156(4): 1256-1263

Woo, H. M., S. Noack, et al. (2010)

Link between phosphate starvation and glycogen metabolism in Corynebacterium glutamicum, revealed by metabolomics
Appl Environ Microbiol 76(20): 6910-6919

Ziegler, C., E. Bremer, et al. (2010)

The BCCT family of carriers: from physiology to crystal structure
Mol Microbiol 78(1): 13-34

Publications in 2009

Krämer, R. and C. Ziegler (2009)

Regulative interactions of the osmosensing C-terminal domain in the trimeric glycine betaine transporter BetP from Corynebacterium glutamicum
Biol Chem 390(8): 685-691

Buchinger, S., J. Strosser, et al. (2009)

A combination of metabolome and transcriptome analyses reveals new targets of the Corynebacterium glutamicum nitrogen regulator AmtR
J Biotechnol 140(1-2): 68-74

Follmann, M., M. Becker, et al. (2009)

Potassium transport in Corynebacterium glutamicum is facilitated by the putative channel protein CglK, which is essential for pH homeostasis and growth at acidic pH
J Bacteriol 191(9): 2944-2952

Follmann, M., I. Ochrombel, et al. (2009)

Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis
BMC Genomics 10: 621

Hanssler, E., T. Muller, et al. (2009)

A game with many players: control of gdh transcription in Corynebacterium glutamicum
J Biotechnol 142(2): 114-122

Heuser, F., K. Marin, et al. (2009)

Improving d-mannitol productivity of Escherichia coli: impact of NAD, CO2 and expression of a putative sugar permease from Leuconostoc pseudomesenteroides
Metab Eng 11(3): 178-183

Jolkver, E., D. Emer, et al. (2009)

Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum
J Bacteriol 191(3): 940-948

Kramer, R. (2009)

Osmosensing and osmosignaling in Corynebacterium glutamicum
Amino Acids 37(3): 487-97

Nentwich, S. S., K. Brinkrolf, et al. (2009)

Characterization of the LacI-type transcriptional repressor RbsR controlling ribose transport in Corynebacterium glutamicum ATCC 13032
Microbiol 155(Pt 1): 150-164

Seibold, G. M., M. Wurst, et al. (2009)

Roles of maltodextrin and glycogen phosphorylases in maltose utilization and glycogen metabolism in Corynebacterium glutamicum
Microbiol 155(Pt 2): 347-58

Youn, J. W., E. Jolkver, et al. (2009)

Characterization of the dicarboxylate transporter DctA in Corynebacterium glutamicum
J Bacteriol 191(17): 5480-8

Publications in 2008

Youn, J.-W., Jolkver, E., Krämer, R., Marin, K., and Wendisch, V.F. (2008)

Identification and characterization of the dicarboxylate uptake system DccT in Corynebacterium glutamicum
J Bacteriol 190: 6458-66

Morbach, S. and Krämer, R. (2008)

Environmental stress response of Corynebacterium glutamicum
in Corynebacterium glutamicum Genomics and Molecular Biology (Burkovski, A., ed.), Caister Academic Press, pp. 313-334

Drath M, Kloft N, Batschauer A, Marin K, Novak J, Forchhammer K. (2008)

Ammonia Triggers Photodamage of Photosystem II in the Cyanobacterium Synechocystis sp. Strain PCC 6803.
Plant Physiol. 147:206-15

Ott, V., J. Koch, et al. (2008)

Regulatory properties and interaction of the C- and N-terminal domains of BetP, an osmoregulated betaine transporter from Corynebacterium glutamicum
Biochemistry 47(46): 12208-12218

Trötschel, C., M. Follmann, et al. (2008)

Methionine Uptake in Corynebacterium glutamicum by MetQNI and by MetPS, a Novel Methionine and Alanine Importer of the NSS Neurotransmitter Transporter Family
Biochemistry 47(48):12698–709

Walter, B., M. Kuspert, et al. (2008)

Dissection of ammonium uptake systems in Corynebacterium glutamicum: mechanism of action and energetics of AmtA and AmtB
J Bacteriol 190(7): 2611-14

Publications in 2007

Krämer, R. (2007)

Production of amino acids: physiological and genetic approaches.
in: Functional Foods and Biotechnology (Shetty et al., ed.), CRC Press Taylor and Francis, pp. 545-582.

Stirnberg, M. Fulda, S., Huckauf, J., Hagemann, M., Krämer, R., and Marin, K. (2007)

A membrane bound FtsH protease is involved in osmoregulation in Synechocystis sp. PCC 6803: the compatible solute synthesizing enzyme GgpS is one of the targets for proteolysis.
Mol. Microbiol. 63,86-102

Lüdke, A., Krämer, R., Burkovski, A., Schluesener, D, and Poetsch, A.(2007)

A proteomic study of Corynebacterium glutamicum AAA+ protease FtsH
BMC Microbiol. 7, 6

Möker, N, Kramer, J., Undern, G., Krämer, R., and Morbach, S. (2007)

In vitro analysis of the two-component system MtrB-MtrA from Corynebacterium glutamicum.
J. Bacteriol. 189, 3645-3649.

Marin, K. and Krämer, R. (2007)

Amino acid transport systems in biotechnologically relevant bacteria.
in:Amino Acid Biosynthesis (Wendisch, V., ed.) Microbiol. Monogr, pp. 290-325, Springer, Heidelberg.

Weinand, M., Krämer, R., and Morbach, S. (2007)

Characterization of compatible solute transporter multiplicity in Corynebacterium glutamicum.
Appl. Microbiol. Biotechnol., 76, 701-708.

Müller, T., Strösser, J., Buchinger, S., Nolden, L., Wirtz, A., Krämer, R., and Burkovski, A. (2007)

Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: Towards the identification of nitrogen control signals
J. Biotechnol. 126, 440-453.

Hänssler, E. Muller, T., Jessberger, N., Volzke, A., Plassmeier, J., Kalinowski, J., Krämer, R., and Burkovski, A.(2007)

FarR, a putative regulator of amino acid metabolism in Corynebacterium glutamicum
Appl. Microbiol. Biotechnol. 76, 625-632.

Özcan, N., Ejsing, C.S., Shevchenko, A., Lipski, A., Morbach, S., and Krämer, R. ((2007)

Osmolality, temperature, and membrane lipid composition modulate the activity of betaine transporter BetP in Corynebacterium glutamicum
J. Bacteriol. 189, 7485-7496.

Möker, N., Reihlen, P., Krämer, R., and Morbach, S. (2007)

Osmosensing properties of the histidine kinase MtrB from Corynebacterium glutamicum
J. Biol. Chem. 282, 27666-27677.

Walter, B., Hänßler, E., Kalinowski, J., and Burkovski, A.(2007)

Nitrogen metabolism and nitrogen control in corynebacteria: variations of a common theme.
J. Mol. Microbiol. Biotechnol. 12, 131-138.

Bramkamp, M., Altendorf, K., and Greye, J.-C.(2007)

Common patterns and unique features of F-type ATPases: a comparative view on the KdpFABC complex from Escherichia coli
Mol. Membr. Biol. 24, 375-386

Seibold, G.M., Dempf, S., Schreiner, J., and Eikmanns B.J. (2007)

Glycogen formation in Corynebacterium glutamicum and role of ADP-glucose pyrophosphorylase.
Microbiology 153, 1275-85.

Seibold, G.M., and Eikmanns, B.J. (2007)

The glgX gene product of Corynebacterium glutamicum is required for glycogen degradation and for fast adaptation to hyperosmotic stress.
Microbiology 153, 2212-20.

Publications in 2006

Carpinelli, J., Krämer, R., and Agosin, E. (2006)

Metabolic engineering of Corynebacterium glutamicum for trehalose overproduction: role of the TreYZ trehalose biosynthetic pathway.
Appl. Environ. Microbiol. 72, 1949-1955.

Schiller, D., Ott, V., Krämer, R., and Morbach, S.(2006)

Influence of membrane composition on osmosensing by the betaine carrier BetP from Corynebacterium glutamicum.
J. Biol. Chem. 281, 7737-7746

Müller, T., Strösser, J., Buchinger, S., Nolden, L., Wirtz, A., Krämer, R, and Burkovski, A. (2006)

Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: towards the identification of nitrogen control signals.
J. Biotechnol. 126, 440-453.

Marin, K., Stirnberg, M., Eisenhut, M., Krämer, R., and Hagemann, M.(2006)

Osmotic stress in Synechocystis sp. PCC 6803: low tolerance towards nonionic osmotic stress results from lacking activation of glucosylglycerol accumulation.
Microbiology 152, 2023-2030.

Silberbach, M., and Burkovski, A.(2006)

Application of global analysis techniques to Corynebacterium glutamicum: new insights into nitrogen regulation.
J. Biotechnol. 126, 101-110.

Fulda, S., Mikat, S., Huang, F., Huckauf, J., Marin, K., Norling, B., and Hagemann, M.(2006)

Proteome analysis of salt stress response in the cyanobacterium Synechocystis sp. strain PCC 6803.
Proteomics 6, 2733-2745.

Müller, T., Walter, B., Wirtz, A., and Burkovski, A. (2006)

Ammonium toxicity in bacteria.
Curr. Microbiol. 52, 400-406.

Bramkamp, M., Weston, L., Daniel R.A., and Errington, J.(2006)

Regulated intramembrane proteolysis of FtsL protein and the control of cell division in Bacillus subtilis.
Mol. Microbiol. 62, 580-591.

Seibold, G.M., Auchter, M., Berens, S., Kalinowski, J., and Eikmanns, B.J. (2006)

Utilization of soluble starch by a recombinant Corynebacterium glutamicum strain: growth and lysine production.
J. Biotechnol. 124, 381-391.